FGF-basic is one of 23 known members of the FGF family. Proteins of this family play a central role during prenatal development, postnatal growth and regeneration of a variety of tissues, by promoting cellular proliferation and differentiation. FGF-basic is a non-glycosylated, heparin-binding growth factor that is expressed in the brain, pituitary, kidney, retina, bone, testis, adrenal gland, liver, monocytes, epithelial cells and endothelial cells. FGF-basic signals through FGFR 1b, 1c, 2c, 3c and 4. Recombinant Murine FGF-basic is a 16.3 kDa protein consisting of 145 amino acid residues.
Manufactured using all Animal-Free reagents.
Source:E.coli
Synonyms:Fibroblast Growth Factor-basic, FGF-2, HBGF-2, Prostatropin
AA Sequence:PALPEDGGAA FPPGHFKDPK RLYCKNGGFF LRIHPDGRVD GVREKSDPHV KLQLQAEERG VVSIKGVCAN RYLAMKEDGR LLASKCVTEE CFFFERLESN NYNTYRSRKY SSWYVALKRT GQYKLGSKTG PGQKAILFLP MSAKS
Purity:≥ 95% by SDS-PAGE gel and HPLC analyses.
Biological Activity:Determined by a cell proliferation assay using Balb/c 3T3 cells. The expected ED50 is ≤ 1.0 ng/ml, corresponding to a specific activity of ≥ 1 x 106 units/mg.
Calculated Molecular Weight:16.3 kDa
Accession Number:P15655
Gene ID:14173
Endotoxin:Endotoxin level is < 0.01 ng/ug of protein (< 0.1 EU/ug)
Not for human use.
Research Interest